Tsvagiridzo yekuongorora yemasampuli emvura ine huwandu hwakasiyana hwemashandisirwo musainzi yehupenyu uye kuongorora kwezvakatipoteredza.Mubasa iri, isu takagadzira compact uye isingadhure photometer yakavakirwa pasimbi waveguide capillaries (MCCs) yekusimbisa kutsunga kwekunyura.Iyo nzira yemaziso inogona kuwedzerwa zvakanyanya, uye yakareba kupfuura kureba kwemuviri kweMWC, nekuti mwenje wakaparadzirwa nemarara akatsetseka simbi pamativi anogona kuve mukati mecapillary zvisinei nekona yechiitiko.Concentrations yakaderera se5.12 nM inogona kuwanikwa uchishandisa zvakajairika chromogenic reagents nekuda kweiyo nyowani isiri-linear optical amplification uye nekukurumidza sampuli switch uye kuona glucose.
Photometry inoshandiswa zvakanyanya kutsvaga kuongororwa kwemasampuli emvura nekuda kwekuwanda kweanowanikwa chromogenic reagents uye semiconductor optoelectronic zvishandiso1,2,3,4,5.Kuenzaniswa neyechinyakare cuvette-based absorbance determination, liquid waveguide (LWC) capillaries reflect (TIR) nekuchengetedza chiedza chekuongorora mukati me capillary1,2,3,4,5.Zvisinei, pasina humwe huri nani huri nani, nzira yemaziso inongoswedera pedyo nehurefu hwemuviri weLWC3.6, uye kuwedzera kweLWC kureba kupfuura 1.0 m ichatambura nekudzivirira kwechiedza chakasimba uye dambudziko guru rekuputika, etc.3, 7. Nezve kune yakatsanangurwa yakawanda-reflection sero ye optical nzira kuvandudzwa, muganhu wekuona unongovandudzwa nechikamu che 2.5-8.9.
Parizvino kune mhando mbiri huru dzeLWC, dzinoti Teflon AF capillaries (ine refractive index ye ~ 1.3 chete, iyo yakaderera pane iyo yemvura) uye silica capillaries yakaputirwa neTeflon AF kana simbi mafirimu1,3,4.Kuti uwane TIR pakusangana pakati pezvinhu zvedielectric, zvinhu zvine yakaderera refractive index uye high light incidence angles zvinodiwa3,6,10.Nezve Teflon AF capillaries, Teflon AF inofema nekuda kweiyo porous chimiro3,11 uye inogona kutora zvidiki zvezvinhu mumasampuli emvura.Kune quartz capillaries yakavharwa kunze neTeflon AF kana simbi, iyo refractive index yequartz (1.45) yakakwirira kudarika yakawanda yemvura samples (eg 1.33 yemvura)3,6,12,13.Kune ma capillaries akaputirwa nesimbi firimu mukati, zvifambiso zvekutakura zvakadzidzwa14,15,16,17,18, asi nzira yekuputira yakaoma, pamusoro pefirimu resimbi ine rough uye porous structure4,19.
Pamusoro pezvo, maLWC ezvokutengeserana (AF Teflon Coated Capillaries uye AF Teflon Coated Silica Capillaries, World Precision Instruments, Inc.) ane zvimwe zvipingamupinyi, se: pakukanganisa..Iyo yakakura yakafa volume yeTIR3,10, (2) T-connector (kubatanidza capillaries, fibers, uye inlet/outlet tubes) inogona kuteya mabubbles emhepo10.
Panguva imwecheteyo, kutsunga kwemazinga eglucose kwakakosha zvikuru kuongororwa kwechirwere cheshuga, cirrhosis yechiropa uye chirwere chepfungwa20.uye nzira dzakawanda dzekuona dzakaita se photometry (kusanganisira spectrophotometry 21, 22, 23, 24, 25 uye colorimetry pabepa 26, 27, 28), galvanometry 29, 30, 31, fluorometry 32, 33, 34, 35, optical 3 polarimetry 3 pamusoro plasmon resonance.37, Fabry-Perot cavity 38, electrochemistry 39 uye capillary electrophoresis 40,41 zvichingodaro.Zvisinei, dzakawanda dzeidzi nzira dzinoda midziyo inodhura, uye kuonekwa kweglucose pane dzakawanda nanomolar concentrations inoramba iri dambudziko (somuenzaniso, kune photometric zviyero21, 22, 23, 24, 25, 26, 27, 28, iyo yakaderera yeglucose).iyo inogumira yaingova 30 nM apo Prussian yebhuruu nanoparticles yakashandiswa se peroxidase mimics).Nanomolar glucose ongororo inowanzodikanwa kune ma molecular-level cellular zvidzidzo senge inhibition yekukura kwegomarara reprostate42 uye CO2 kugadzirisa maitiro eProchlorococcus mugungwa.
Nguva yekutumira: Nov-26-2022